Malware normally propagates to users and computers through files attached to email or hiding within legitimate traffic. Attackers have taken advantage of social media to distribute malware. While most malicious codes are hidden in small sized files that make them easier to spread over the Internet, malware can be embedded in all file sizes. This document offer some insight on how malware inspection performance is related to the size of malware-infected files and how different scanning methods can help to strike a balance between performance and security.